TB-500
Pathway Genes
Biomeme does not prescribe, supply, recommend or evaluate this therapy. This page describes which genes it acts on, not whether you should take it.
There are no published human clinical trials of this peptide.
TB-500 is a synthetic fragment of thymosin beta-4, studied in preclinical models of tissue repair. This page describes the genes those studies implicate and what a transcript panel can and cannot say about them.
Tracked Physiological Dimensions
On the Advanced Transcriptomics Dashboard, TB-500 is tracked across the musculoskeletal dimension.
Cytoskeletal and Repair Gene Regulation
TB-500 is a synthetic peptide based on the actin-binding domain of thymosin beta-4. In preclinical models, it has been studied for its role in cell motility and cytoskeletal organization.
This panel reports circulating leukocyte transcription of ACTB, FGF2, MMP2, and MMP9. Note that MYOD1 is a skeletal-muscle transcript and is not recoverable at meaningful abundance from a blood draw; it is studied in tissue research contexts.
Key Target Genes
Actin Beta Cytoskeletal Structure
Drives actin polymerization, crucial for cell migration, cellular architecture, and tissue repair.
Myoblast Determination Protein 1 Satellite Cell Activation (Research Reference)
Induced early after satellite cell activation in muscle tissue models; not recoverable from whole blood.
Fibroblast Growth Factor 2 Growth Factor Signaling
Stimulates cell growth, vascular sprout formation, and tissue regeneration at injury sites.
Matrix Metalloproteinases 2 & 9 Extracellular Remodeling
Extracellular endopeptidases involved in extracellular matrix remodeling.
The Biomeme Molecular Ecosystem
From deep whole-transcriptome sequencing in the laboratory to rapid point-of-care instrumentation in the field.
High-Depth RNA Sequencing
Processed at One Health Labs, Biomeme's CLIA-certified laboratory, using Illumina NovaSeq high-depth paired-end RNA sequencing. Samples are collected in venous PAXgene blood RNA tubes to stabilize cellular transcription at the moment of draw.
Biomeme/5 Handheld Platform
Beyond central-lab genomics, Biomeme engineers patented, battery-powered real-time PCR instruments. Our deployable hardware brings decentralized molecular detection directly to the field and clinical points of care.
Scientific Citations (1)
- [1] Dumont NA, Bentzinger CF, Sincennes MC, Rudnicki MA. Satellite Cells and Skeletal Muscle Regeneration. Compr Physiol. 2015;5(3):1027-1059.
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ABOUT THESE PANELS
Biomeme's wellness transcriptomic panels are general wellness products. They report gene activity to support a healthy lifestyle. They are not intended to diagnose, treat, cure, mitigate or prevent any disease or condition, and they are not a substitute for evaluation by a licensed healthcare professional. Results describe the state of the measured transcripts at the moment the sample was taken.