Molecular Target Library

Master regulator of blood vessel formation and tissue repair.

Potent growth factor driving fibroblast proliferation and wound healing.

Enzyme producing nitric oxide for vascular health and blood flow regulation.

Master transcription factor coordinating the cellular response to low oxygen.

Primary mediator of growth hormone's anabolic effects throughout the body.

Nuclear receptor that mediates testosterone's effects on gene expression.

Myostatin antagonist that promotes muscle growth and metabolic health.

Enzyme converting testosterone to estradiol — critical for hormonal balance monitoring.

Dual-role cytokine — both pro-inflammatory driver and exercise myokine.

Primary pro-inflammatory cytokine driving acute and chronic inflammatory signaling.

Master transcription factor controlling the inflammatory gene expression program.

Receptor for GLP-1 incretin hormones — the target of semaglutide and tirzepatide.

Master energy sensor that coordinates metabolic adaptation to energy stress.

Insulin-responsive glucose transporter — the endpoint of metabolic signaling.

Master regulator of the antioxidant defense system.

Key growth factor for neuroplasticity, learning, and mood regulation.

Immune checkpoint molecule whose upregulation predicts sepsis onset in trauma patients.

Antigen presentation molecule — its downregulation signals immune paralysis in sepsis.

Neutrophil-derived alarmin — one of the earliest transcriptomic signals of immune activation.

Primary anti-inflammatory cytokine — its expression ratio with pro-inflammatory markers defines sepsis phenotype.

NAD+-dependent deacetylase central to metabolic regulation and aging.

Master regulator of mitochondrial biogenesis and energy metabolism.

Rate-limiting enzyme in the NAD+ salvage pathway — the gateway to sirtuin activation.

Mitochondrial sirtuin governing oxidative metabolism and ROS defense.