FGF2
Fibroblast Growth Factor 2
Also known as: bFGF, Basic FGF
Potent growth factor driving fibroblast proliferation and wound healing.
Biological Function
FGF2 stimulates fibroblast proliferation, endothelial cell migration, and extracellular matrix deposition — all critical components of wound healing and tissue repair. It signals through FGF receptors to activate MAPK and PI3K pathways. FGF2 works synergistically with VEGF during angiogenesis and is a key mediator of the proliferative phase of wound healing.
Why Biomeme Monitors This Target
FGF2 is a core molecular target for tissue repair peptides like BPC-157. Monitoring FGF2 expression alongside VEGF provides a more complete picture of whether peptide therapies are activating the wound healing gene program or producing no detectable molecular change.
Expression Context
Upregulated during wound healing, tissue injury, and bone fracture repair. Expressed in most tissues at low baseline levels. Dysregulated expression is associated with fibrotic diseases.
Signaling Pathway
Quick Facts
- Symbol
- FGF2
- Category
- Angiogenesis & Tissue Repair
- Applications
- Wellness
- Linked Therapies
- 1
Related Targets
Monitor FGF2 Expression.
Biomeme's multiplexed platform can include FGF2 in a custom panel alongside up to 47 other molecular targets — in a single rapid run.
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